What is a Low Histamine Diet? A low histamine diet is a temporary, symptom-guided approach that reduces foods most likely to contain substantial histamine, especially aged, fermented, preserved, or poorly stored foods. Frequently Asked QuestionsIs a Low Histamine Diet The Same as a Low FODMAP Diet? No, Low FODMAP limits certain fermentable carbohydrates, while low histamine targets histamine exposure. Can Children Follow a Low Histamine Eating Plan?