Yet a new review of more than 350 studies on protein restriction and aging suggests that many people may gain more from eating less protein, and that lower intake could sometimes contribute to a longer life. The researchers conclude that protein restriction can improve metabolism, alter the way cells react to nutrients, limit cellular damage, and help cells maintain normal function. Across the research, lower protein intake was linked to better metabolic function, altered nutrient signaling, reduced cellular damage, and improved maintenance of healthy cells. A Hormone Linked to LongevityOne important factor is fibroblast growth factor 21 (FGF21), a hormone that increases when protein intake falls. Lower protein intake also increases FGF21 levels in humans.