Why Ovarian Cancer Often ReturnsNearly all ovarian cancer patients receive platinum-based chemotherapy, and the initial response is often strong. Previous studies have indicated that cancer cells surviving chemotherapy may help drive recurrence by releasing a complicated mixture of signaling molecules. The team collected molecules produced by chemotherapy-surviving cells and exposed other cancer cells to them. Their analysis showed that the surviving cancer cells produced fructose and used it as a signal that encouraged neighboring cells to spread. How Fructose Helps Cancer Cells EscapeThe team next investigated how fructose makes cancer cells more likely to spread.