By: Kim Radcliffe, DHA, MHA, PT, SVP, Product Management, EnlyteComplex Regional Pain Syndrome, or CRPS, can change the course of an upper extremity claim fast. CRPS can occur in many parts of the body, but the upper extremity, especially the hand and wrist, is particularly high risk. Work Injuries Adjusters Should WatchIn workers’ compensation, CRPS most often shows up after common upper extremity injuries. Crush injuries, carpal injuries and post-surgical cases like carpal tunnel release also carry risk. The primary treatment for CRPS is active rehabilitation, specifically occupational and physical therapy.