OPKO Health (NASDAQ:OPK – Get Free Report) and Zicix (OTCMKTS:ZICXD – Get Free Report) are both small-cap healthcare companies, but which is the better investment? Get OPKO Health alerts:Insider and Institutional Ownership64.6% of OPKO Health shares are owned by institutional investors. Valuation and EarningsGross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio OPKO Health $587.90 million 1.71 -$225.68 million ($0.09) -15.00 Zicix N/A N/A N/A ($100.14) -0.00This table compares OPKO Health and Zicix”s top-line revenue, earnings per share (EPS) and valuation. Net Margins Return on Equity Return on Assets OPKO Health -12.40% -5.88% -3.83% Zicix N/A N/A N/AAnalyst RecommendationsThis is a summary of current ratings for OPKO Health and Zicix, as reported by MarketBeat.com. Given OPKO Health’s stronger consensus rating and higher possible upside, equities analysts plainly believe OPKO Health is more favorable than Zicix.