A guide to peptides vs. testosterone therapy should begin there, since this split shapes lab follow-up, symptom tracking, fertility planning, and risk review over time. What Testosterone Therapy DoesTestosterone therapy treats confirmed low testosterone when symptoms and lab findings align. Testosterone therapy can produce a clearer improvement in libido, morning energy, strength, and mood when a deficiency is present. Testosterone evaluation often includes morning total testosterone levels, free testosterone, luteinizing hormone, estradiol, a complete blood count, and metabolic markers. Testosterone therapy can lower sperm production because the brain may reduce signals that stimulate the testes.