Hair loss can be sparked by everything from your genetics to your stress levels, making it hard at times to pinpoint what’s fueling the shedding. None of the participants had a documented history of alopecia (the medical term for hair loss). The difference was noticeable by six months, when 1.55% of tirzepatide users developed hair loss compared to 1.24% of semaglutide users. “In our study, hair loss was uncommon overall, but it was a real signal and should not be brushed aside.” (It's also worth noting that, by some estimates, roughly 50% of women will deal with hair loss in their lifetimes anyways).