Fact vs. Fiction: Separating the Myths from the Science Behind GLP-1 MedicationsFew medications have generated as much conversation and as much misinformation as GLP-1 medications. Dr. Schneider: Although many people first heard about these medications for weight loss, GLP-1 medications have been used to treat Type 2 diabetes for years. FACT: Muscle loss can happen with any significant weight loss but it isn’t inevitable. GLP-1 medications aren’t a miracle cure or a shortcut. GLP-1 medications have transformed obesity treatment, but they aren’t a shortcut or a miracle cure.