A new report highlights which animals are most likely to kill someone in each U.S. state – but what is Mississippi’s? The deadliest animal in the Magnolia State, however, was in a different category from the others already listed, but it makes up the most-represented group on the list. The cottonmouth snake takes the cake for Mississippi as the animal that is most likely to lead to death. Found across the state, cottonmouth venom has been medically documented numerous times in Mississippi to have serious health implications. At the end of the day, it’s a good policy to be aware of your surroundings in Mississippi when near water to avoid contact with the state’s deadliest animal.