“Peptides and retinol can both support smoother, firmer-looking skin, but they work in different ways,” Dr. Phillips distinguishes. Depending on the type, they may support collagen production, hydration, or the skin barrier. Retinol is a vitamin A derivative that increases skin cell turnover and stimulates collagen production, with stronger evidence for improving fine lines, uneven texture, and post-acne marks.” For minimizing the appearance of fine lines and wrinkles, there is a wealth of scientific evidence surrounding retinol. Peptides tend to be gentler and may be a better starting point for people with sensitive or reactive skin.”