A new study developed a method for developing 64 different DNA sequences in parallel using a silicon chip, finely-tuned electrodes, and a water-based process known as enzymatic DNA synthesis. This new process relies on a gentler, more eco-friendly method of synthesis known as “enzymatic DNA synthesis” and primarily uses water instead of chemicals, mimicking more closely how living cells build DNA. This far exceeds previous enzymatic DNA synthesis approaches that could only reproduce a dozen sequences or so, and pushes the technology toward being a true alternative to phosphoramidite chemistry. “That is why enzymatic synthesis in water can matter. With this new chip, scientists are one step closer to making that dream a reality.