CancerCzech researchers describe new CD73 inhibitorsScientists at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences have reported 6-(Het)aryl-7-deazapurine ribonucleoside bisphosphonates acting as 5’-nucleotidase (CD73) inhibitors potentially useful for the treatment of cancer, autoimmune diseases, inflammatory disorder, pain, cardiovascular diseases, transplantation and neurological disorders.