A serious Route 101 crash in Keene sent one driver to a Lebanon hospital by helicopter and caused a second five-vehicle crash. Emergency crews respond to a serious crash on Route 101 in Keene Tuesday evening that left one driver critically injured. KEENE, N.H. (MyKeeneNow) A serious two-vehicle crash on Route 101 in Keene Tuesday evening left one driver critically injured and prompted a roughly 2½-hour road closure, according to Keene police. Investigators said a vehicle traveling west on Route 101 crossed the center line and struck an embankment along the eastbound side of the road. The crash investigation led to a lengthy closure of Route 101.