Even if the gum reduced oral HPV in people, that would not automatically translate into fewer cancers. Why Oral HPV Is a Growing ConcernHead and neck squamous cell carcinoma begins in the tissues lining the mouth and throat. There is no routine screening test for oral HPV comparable to cervical screening, and no established way to treat an infection that has been detected. Extracts from a bioengineered chewing gum reduced HPV by about 93% in saliva samples and 80% in oral rinse samples from head and neck cancer patients, tested in the laboratory. Why does oral HPV matter?