The dopamine theory of schizophrenia holds psychiatry in sway much like the serotonin theory of depression did for decades. Garson vividly dramatizes the era of the rise of biological psychiatry that produced this change in clinical practice. Amphetamines induced psychosis by increasing dopamine activity; antipsychotics cured psychosis by reducing dopamine activity; therefore, psychosis or schizophrenia was caused by too much dopamine. The sheer volume of brain research convinced people that schizophrenia is a brain disease. The biological view portrays psychosis as the hollow expression of a disease process and the sufferer as its walking manifestation.