Most coverage described the product as a 650 mg acetaminophen and 220 mg naproxen sodium pill. The FDA's own announcement specifies the approved tablet strength as 325 mg of acetaminophen and 110 mg of naproxen sodium. Taken as directed at two tablets twice daily, the product delivers 1,300 mg of acetaminophen and 440 mg of naproxen sodium over 24 hours. Tylenol with Naproxen, a tablet containing 325 mg of acetaminophen and 110 mg of naproxen sodium, dosed every 12 hours, for adults and children 12 and older. The manufacturer describes a dose as delivering 650 mg of acetaminophen and 220 mg of naproxen sodium, which corresponds to two of the approved tablets.