But now an even bigger challenge: How to remove waterproof mascara without losing any eyelashes in the process? Waterproof mascara is designed to last the night and then some. Want to know how to remove waterproof mascara without damaging your lashes? What is waterproof mascara? The 14 Best Waterproof Mascaras, According to Glamour Editors Gallery 14 Slides View SlideshowHowever, these sweat-proof, smudge-proof ingredients also mean that removing waterproof mascara requires extra care.