Out-of-network drug costs 67% higher in workers comp: EnlyteInjured workers’ prescriptions filled outside pharmacy networks cost an average of 67% more than comparable in-network medications, according to an analysis released Friday by Enlyte. The report found the largest price disparities among muscle relaxants, which cost 69% more when dispensed out of network, and topical medications, which averaged 62% higher costs. While opioids remained the largest therapeutic class by spend and prescription volume within Enlyte’s in-network pharmacy program, the out-of-network market looked markedly different. Florida, Illinois, New York, Pennsylvania and Tennessee represented the highest pharmacy spending in the dataset, with costs per script and percentage of out-of-network spending varying. Unlike most jurisdictions, in-network prescriptions there carried higher average costs than out-of-network fills because some prescribers selected higher-priced versions of drugs included on the state’s workers compensation formulary.