Just when we thought skin care trends couldn’t get any fishier (cue the salmon sperm craze of 2025), TikTokers tout their latest catch: sardines. That said, no one fish is the secret to healthy skin; trout, herring, salmon and mackerel also all deliver omega-3s. Dr. Anil Shah, a double board-certified plastic surgeon, attributed rising interest in sardines, specifically, to the “inside-out” wellness methodology and regenerative skin care. Indeed, PDRN skin care is different from salmon and sardine skin care in that the former is delivered topically (or injected in the case of Rejuran, which is only administered in Seoul) and the latter are consumed orally. I would pay more attention to the sodium, since smoked, brined and flavored tins can be surprisingly salty,” Dr. Palm continued.