(Photo credit: Stephen Lew-Imagn Images)Mac Jones is in line to make a second straight start under center for the San Francisco 49ers after the team listed quarterback Brock Purdy as questionable for Sunday's game against the Arizona Cardinals. Purdy came away from the season-opening win against Seattle with toe and left shoulder injuries, his toe being the bigger concern. 'I think it's highly unlikely that (Purdy) will start,' Shanahan said. The 49ers will need to know by Saturday whether Purdy will be active as the No. The 49ers also listed receiver Jauan Jennings (ankle, shoulder) and guard Connor Colby (groin) as questionable.