The daily capsule is made almost entirely from vitamin B3 to trigger NAD+ production in a form that optimises absorption. The daily capsule is made almost entirely from vitamin B3 to trigger NAD+ production in a form that optimises absorption. At this point, you may be wondering why you would supplement NMN to make NAD+ when you can simply supplement NAD+ and cut out a step? “Much of the current research has focused on precursors such as NMN and nicotinamide riboside (NR), which appear to increase NAD+ levels more efficiently than taking NAD+ directly,” flags Smith. Widely viewed as one of the most effective precursors to NAD+, this supplement contains NMN (nicotinamide mononucleotide) a naturally occurring derivative of vitamin B3.