Researchers break diffraction barrier in super-resolution microscopy New U-STORM imaging technology lets scientists view molecular structures in subatomic detail - about 1,000 times clearer than traditional dyes - while making the microscope process much simpler. An open-access description of the study was published in Nature Nanotechnology ("Spontaneous and indefinite blinking in upconverting nanoparticles for ångström-precision multicolour super-resolution imaging"). MIT researchers developed a groundbreaking super-resolution imaging platform called U-STORM (Upconversion enabled Stochastic Optical Reconstruction Microscopy). Unlike conventional multicolor super-resolution imaging, which requires multiple expensive lasers and meticulous optical alignment, U-STORM can operate with just one near-infared laser. To obtain images with multiple colors, rather than capturing images sequentially over multiple rounds, U-STORM captures multiple colors simultaneously.