Karen Susan Charlton, 64, of Ambridge, passed away peacefully at home on July 31st, 2026. In addition to her parents, she was preceded in death by her brother and sister-in-law, Bill and Donna Gaertner. She was the devoted wife of Lawrence Charlton and a loving mom to Parker Charlton (Natasha Charlton), Abbie Charlton (Buddy Cowles), and Preston Charlton (Jordan Charlton). She is also survived by her sisters, Peggy Watson (Rich) and Linda McAfee (Bob) and her in-laws, Scott Charlton (Susan), Kevin Charlton, and Heather Charlton, along with many nieces and nephews. Karen was a member of One in Christ Church in Ambridge and lived her life rooted in faith and family.