A nuclear stress test is one of the tools doctors use to answer it. This blog covers what a nuclear stress test is, when doctors recommend one, and what to expect if it’s suggested. Nuclear Stress Test: Before, During, and AfterPreparation helps improve image accuracy and reduces possible discomfort during the procedure. Nuclear Stress Test Results: What Happens NextAfter the nuclear stress test, a specialist reviews the scans to see how the heart performed under exertion. A nuclear stress test is generally considered safe, but like any medical procedure, it has possible risks.