Early vitrectomy surgery treatment for a rare eye condition, acute endophthalmitis, can be potentially more beneficial to patients' vision compared with the current antibiotic-first approach, finds a study led by University College London (UCL) and Moorfields Eye Hospital researchers. It is a rare condition (one in 1,000 to 2,000 patients) but is a devastating complication from any form of eye surgery or eye injection, and can lead to sight loss and blindness. Thirty years ago, research indicated the potential benefits of immediate vitrectomy for patients developing endophthalmitis after cataract surgery, but this is seldom carried out. Early vitrectomy also showed lower rates of non-serious adverse events (47% vs 68%) and retinal detachment. Early vitrectomy and intravitreal antibiotics for post-operative exogenous endophthalmitis (EVIAN): a randomised control trial of feasibility.