Nearly three quarters of the 67 countries used more antibiotics than the researchers estimated were needed. Antibiotics in this group are broad-spectrum drugs that come with a greater risk of causing antibiotic resistance and should generally be reserved for defined infections. The study also found some higher-income countries used substantially more antibiotics than their infection burden appeared to justify. In contrast, lower-income regions often carry greater burdens of serious infection and resistance, while lacking access to effective antibiotics. These actions may appear mundane, but fewer infections mean fewer opportunities for antibiotics to be used and resistance to develop.