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After anesthesia: Female brains recover differently from ketamine
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Instanz: TeilenTeilen:After anesthesia: Female brains recover differently from ketamineAndreas Rothe Communications, Events and Science EducationInstitute of Science and Technology Austria31.07.2026 20:00During ketamine anesthesia, the brain’s nerve cells fall silent—as consciousness returns, they begin to reconnect.
Microglia – the brain’s guardians and glueAs early as 2017, Sandra Siegert’s group at ISTA noticed that male and female mice respond differently to ketamine anesthesia—more precisely, their microglia do.
Surprisingly, as female mice recovered from anesthesia, microglia began forming prolonged contacts with neurons, coinciding with the onset of synaptic remodeling and plasticity.
Copyright: © Siegert group / ISTAtime-lapse imaging of microglia-neuron interaction dynamics before and after ketamine anesthesia in female mice.
time-lapse imaging of microglia-neuron interaction dynamics before and after ketamine anesthesia in female mice.