There are a lot of ways to consider the Indianapolis Colts defense in 2025, but most point in the same direction. Throw in major rotational backups Neville Gallimore, Samson Ebukam and Tyquan Lewis, and you are missing more than 5,500 defense snaps from last year. Indianapolis Colts 2026 defense broken down by position groupSo the question is, will these wholesale changes actually make the defense better? Though he continued to log major snaps, he just never seemed to fit into Anarumo’s defensive schemes. Verdict: the sameSimply having a healthy Sauce Gardner on the field for 17 games should make the Colts’ defense better in 2026.