The Highest and Lowest Median Incomes in Americasirichai_ec2 sirichai_ec2Nobody wants to make less than the median income in their state or the national median income. According to a recent study from playcasino.com, the state with the highest median income is Massachusetts at $104,828 a year. The state with the second lowest median income is West Virginia at $60,798, and the third lowest state is Louisiana at $60,986. What is Colorado's Median Income? Nitiphonphat NitiphonphatColorado has one of the higher median incomes in the country, coming in as the eighth highest in the nation with a median income of $97,113.