Oral mucosal wound repair remains a significant clinical challenge, as the humid and highly dynamic oral microenvironment creates conditions that limit the effectiveness of conventional treatment strategies. After being injected onto oral wounds, the precursor rapidly gelled in situ under ultrasound stimulation, enabling precise and stable adhesion to the mucosal tissue. Reading tip:Bio-based coatings The EC Tech Report “”Bio-based Coatings“” is a hand-picked compilation of all the key aspects concerning bio-based coatings, offering the latest technical developments. By integrating in situ gelation, stable mucosal adhesion and active wound-healing promotion into a single bio-based material, the UPLA bioadhesive represents a novel candidate for clinical oral mucosal wound repair. Source: Wei, Y. et al., An ultrasound-responsive lipoic acid-based bioadhesive for oral mucosal wound repair.