Health experts call for greater inclusion of pregnant women in vaccine clinical trials to improve safety data, equitable access, and evidence-based healthcare decisions. Pregnant women have historically been excluded from many vaccine clinical trials due to concerns about potential risks to mothers and babies. Researchers and global health organizations argue that excluding pregnant women from trials can also delay access to important health interventions. Pregnant women faced uncertainty about vaccine safety because early vaccine trials generally did not include them, creating challenges for public health guidance and individual decision-making. Ensuring that pregnant women are represented in clinical trials can help create stronger evidence, improve confidence in vaccination programmes, and protect maternal and infant health worldwide.