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New Therapeutic Targets Identified in Pulmonary Fibrosis
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European Medical Journal
LACTYLATION related genes may offer new therapeutic targets for idiopathic pulmonary fibrosis, according to multiomics research.
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible interstitial lung disease associated with high mortality.
Although lactylation, a recently identified posttranslational modification, has been linked to inflammation and tissue fibrosis, its contribution to IPF remains incompletely understood.
New Therapeutic Targets in IPF IdentifiedThe researchers analyzed transcriptomic and single cell sequencing data from lung tissue collected from patients with IPF and healthy controls.
Identification and functional validation of lactylation-related hub genes in idiopathic pulmonary fibrosis based on multi-omics analysis.