Widely used GLP-1 drugs, including Ozempic and Mounjaro, may carry an unexpected downside: a small but measurable increase in hair loss. Researchers used statistical methods to account for age, sex, ethnicity, pre-existing conditions, body mass index, other medications, and additional factors that might influence hair loss. GLP-1 users had a 53% higher risk of this form of hair loss than SGLT-2 inhibitor users and a 72% higher risk than DPP-4 inhibitor users. One possibility is that the drugs affect hair indirectly through rapid weight loss rather than acting directly on hair follicles. Significant weight loss can push more hairs than usual into a resting phase, leading to increased shedding several months later.