SEX DIFFERENCES in the cancer proteome patterns have been identified across eight cancer types, with lung adenocarcinoma showing the largest number of proteins with differential abundance between male and female patients. Although sex differences in cancer incidence, progression and treatment response are well established, the impact of sex on the cancer proteome has remained poorly understood. Cancer Proteome Differences Varied Between Tumour TypesResearchers retrospectively analysed 1,590 proteomes from eight cancer types included in the Clinical Proteomic Tumor Analysis Consortium cohorts. Sex-Disaggregated Data Could Improve Cancer ResearchThe researchers found that sex differences in cancer proteome profiles varied between tumour types. Sex differences in the cancer proteome.