Are your patients experiencing significant discomfort during cesarean delivery under spinal anesthesia? ConclusionFor anesthesiologists and obstetric teams, remimazolam-nalbuphine offers an evidence-based approach to reducing intraoperative discomfort and improving the cesarean delivery experience. Key pointsRemimazolam-nalbuphine infusion reduced VTR incidence from 41.7% to 5.6% during cesarean delivery under spinal anesthesia. This regimen is a promising, safe adjunct for intraoperative comfort in cesarean delivery; further studies should confirm neonatal outcomes. Intraoperative remimazolam-nalbuphine infusion reduces visceral traction response during cesarean delivery: a randomised trial.