GastrointestinalNovel antifibrotic Arenarine D derivative reportedChronic liver injury promotes hepatic fibrosis through the activation of hepatic stellate cells and excessive extracellular matrix deposition, a process that can progress to cirrhosis and liver cancer. Researchers from Xiamen University used Arenarine D, a natural product isolated from the endophytic fungus Pallidocercospora crystallina, as the starting point for the development of novel antifibrotic agents.