Your prescriber will use your current daily insulin dose to determine your starting dose for weekly insulin. Know how to inject once-a-week insulinInjecting once-a-week insulin is similar to administering daily insulin. 3. Review how to switch from once-a-day to once-a-week insulin with your prescriberYou can switch from a once-daily, long-acting (basal) insulin, such as Lantus (insulin glargine), to a once-a-week insulin. Dispose of once-a-week insulin pens and pen needles in a sharps containerIt’s important to dispose of your once-a-week insulin pens and pen needles properly. Injecting weekly insulin is similar to administering daily insulin, and weekly and daily insulins have similar storage and disposal instructions.