The musculoskeletal system (MSK) is often one of the first areas where students begin to appreciate the connection between structure and function in medicine. Why MSK matters in medical educationThe MSK system provides an ideal foundation for helping students think like future physicians. The MSK module is designed as an interdisciplinary study of the anatomical, histological, physiological, developmental, and pharmacological principles of the skeletal and muscular system. For this reason, the Musculoskeletal System module plays an important role in preparing students for the clinical years and beyond. For students beginning their medical education, the MSK curriculum is often a reminder that medicine is both detailed and deeply human.