Interest in testosterone replacement therapy keeps climbing, and the TRAVERSE trial remains the largest randomized test of its cardiovascular safety. The TRAVERSE trial is the largest randomized controlled study designed to test whether testosterone replacement therapy raises the risk of major heart problems in men with confirmed hypogonadism. Estrogen loss is part of the answer, but it’s not the whole […]Does Testosterone Therapy Increase Heart Attack or Stroke Risk? Who Was Included in the Traverse Testosterone Study? Pulmonary embolism occurred in 0.9 percent of testosterone patients versus 0.5 percent of placebo patients.