Sandra Oh made a rare comment about her decision to exit Grey’s Anatomy amid salary renegotiations. Related: Grey’s Anatomy’s Biggest Exits Over the Years Katherine Heigl, Patrick Dempsey, Justin Chambers and more stars have left Grey’s Anatomy — for various reasons. Created by Shonda Rhimes and starring Ellen Pompeo, Grey’s Anatomy debuted on ABC in 2005. Before her exit, Oh starred on Grey’s Anatomy from its debut in 2005 until 2014. The upcoming series will be cocreated, written and executive produced by Shonda Rhimes and Grey’s Anatomy showrunner Meg Marinis.