Okomfo Anokye Senior High School has secured a return to the National Science and Maths Quiz (NSMQ) championship after a dramatic victory in the Ashanti Regional Qualifiers, ending a two-year absence from Ghana's biggest academic competition. Okomfo Anokye SHS finished with 47 points, narrowly ahead of Namong SHS, which scored 44 points. Effiduase Senior High Commercial School placed third with 35 points, Agric Nzema SHS finished fourth with 30 points, while Dadease Agric SHS ended the contest with 22 points. The victory marks a significant comeback for Okomfo Anokye SHS, which first announced itself on the national stage in 2023 after defeating Asanteman SHS in a memorable Ashanti regional derby to secure its maiden NSMQ qualification. The contest remained finely balanced until the closing stages before Okomfo Anokye SHS held its nerve in the decisive riddle round to clinch qualification.