And what can you do to keep chronic inflammation at bay? Chronic inflammation starts the same way, as a reaction to your body being “invaded.” The difference is that chronic inflammation doesn’t resolve. As of now, though, there is no drug that is FDA-approved for chronic inflammation in general. And eat fish twice a week—it’s a great source of heart-healthy omega-3 fatty acids, which can slow the process of your body making the substances that cause chronic inflammation.