Alec Pierce, WR, Indianapolis Colts14 of 15AP Photo/Zach BolingerColts receiver Alec Pierce was one of the NFL's most explosive receivers in 2025, leading the NFL in yards per catch for the second consecutive season. The hope is Pierce will be back by Week 1, though his recovery timeline might not cooperate. "The return timeline, which Pierce said can range from four to six months, could keep him out well into training camp and past the preseason," ESPN's Stephen Holder wrote in June. Best-Case ScenarioPierce is back on the practice field at the tail end of training camp and is able to physically prepare himself for Week 1. Worst-Case ScenarioWhile Pierce doesn't need to miss a full month on the PUP list, he still misses games to open the season while working his way back into game shape.