This suggests there is a ‘Goldilocks’ zone of IGF-1 levels, according to Andrea Zangara, Scientific Communication Advisor at EuroMed, with EuroMed’s pomegranate extract (marketed as Pomanox) promoting a potentially beneficial increase. It has therefore been suggested that telomere length measurement could serve as a promising clinical tool for age-related diseases. The researchers therefore set out to discover whether supplementation with pomegranate extract, which is high in polyphenols, could impact telomere length and circulating IGF-1 levels. randomly assigned 72 participants between the ages of 55 and 70 to receive either pomegranate extract (Pomanox) or placebo (maltodextrin) for 12 weeks. “Effects of Pomegranate Extract on IGF-1 Levels and Telomere Length in Older Adults (55–70 Years): Findings from a Randomised Double-Blinded Controlled Trial."