The Brief Nationwide measles cases hit 2,318 on Friday, marking the highest surge since 1991, the CDC reported. State Surgeon General Joseph Ladapo, who opposes vaccine mandates, calls the measles vaccine effective. Nationwide measles outbreakWhat we know:Data released on Friday by the CDC shows 2,318 measles cases across the nation. "The measles vaccine happens to be an effective vaccine against measles." Vaccine mandates debateWhat we don't know:Last year, Florida Surgeon General Dr. Joseph Ladapo and Governor Ron DeSantis held a press conference in Tampa vowing to end all vaccine mandates in Florida.