If you’re on a GLP-1 medication such as semaglutide (Ozempic) or tirzepatide (Mounjaro) for type 2 diabetes, or semaglutide (Wegovy), tirzepatide (Zepbound), or orforglipron (Foundayo) for weight loss, you probably know that your food and beverage choices make a big difference in how well you do on these drugs. Certain foods and drinks tend to worsen GLP-1 side effects like diarrhea, nausea, and constipation, which result from changes in the speed at which your stomach empties. Also problematic are foods and drinks that fill you up with “empty” calories because they might displace options that really deliver on protein, fiber, and other nutrients — essential for people on GLP-1s, who have limited appetites. That doesn’t mean you should label certain choices “good” or “bad,” but knowing which food and drinks to limit and what to reach for instead can help ensure you’re feeling good and achieving your health goals.