Ichimaru Pharcos recently launched PeoGlow, a natural active ingredient derived from peony root designed to address skin tone unevenness linked to the glycation process — specifically the interaction between Advanced Glycation End Products (AGEs) and their receptors (RAGE). This mechanism is now understood to be a root cause of uneven skin tone, affecting both melanocytes and keratinocytes, per the company. Key Claims and BenefitsKey product claims and benefits supported by the ingredient include the following. Inhibits AGEs-RAGE interactionReduces AGEs-related brown pigmentationDisrupts AGEs-RAGE signaling associated with black and gray toneImproves overall skin tone uniformityApplicable across facial and body care, PeoGlow is said to be ideal for skin brightening, anti-aging, under-eye treatments, hand creams and body creams. Technical DetailsAdditional formulating considerations are:Form: Yellowish brown to brown liquid with a characteristic odorRecommended dosage: 1%Safety: Toxicity and safety data availableRegulatory: JSQI approved, Chinese IECIC 2021 listed, halal certifiedPatent: Pending in JapanWith PeoGlow, Ichimaru Pharcos aims to offer a scientifically backed approach to correcting brown, black and gray discoloration for a clearer, more even-toned complexion.