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The Gut as a Key Player in Immunotherapy for MS - multiple sclerosis therapy harnesses protective gut immune cells
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Pressemitteilungen - idw - Informationsdienst Wissenschaft
Instanz: TeilenTeilen:The Gut as a Key Player in Immunotherapy for MS - multiple sclerosis therapy harnesses protective gut immune cellsDr. Inka Väth Public Relations and Corporate CommunicationUniversitätsklinikum Bonn23.07.2026 10:17B-cell depletion therapies, in which B cells of the immune system, which may drive disease activity in multiple sclerosis (MS), are temporarily removed, have contributed significantly to improved treatment for patients in recent years.
Surprisingly, the treatment appears to exert part of its beneficial effect by mobilizing regulatory immune cells that naturally reside in the gut.
To this end, the first authors, Dr. Tradite Neziraj and Dr. Elisabeth Pössnecker, analyzed immune cells from various tissues.
Rather than simply removing harmful immune cells, the treatment may also help recruit beneficial immune cells from the gut.
This discovery opens up new possibilities for developing future therapies that harness beneficial gut immune cells in MS and other inflammatory diseases.