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From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
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Pressemitteilungen - idw - Informationsdienst Wissenschaft
Instanz: TeilenTeilen:From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sitesDr. Nicola Wittekindt Presse- und ÖffentlichkeitsarbeitDeutsches Zentrum für Infektionsforschung23.07.2026 12:38Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a remarkable clinical case in the New England Journal of Medicine.
The case began with a chronic urinary tract infection caused by Klebsiella pneumoniae, a common pathogen responsible for nosocomial infections.
Aside from increasingly virulent infections, hetervirulence may also promote chronic infections.
However, virulent subpopulations are even more difficult to detect because bacterial virulence traits are not yet part of standard diagnostics.
Klebsiella Brain Abscess and Evolution of Heterovirulence in the Urinary Tract.