The 64-year-old also said she recently underwent a faceliftUS talk show host Rosie O’Donnell said “Mounjaro changed my life” after losing nearly 30kg on the weight-loss drug. US chat show host Rosie O’Donnell and singer Boy George (PEYTON MATT PEYTON/PA)“Mounjaro changed my life. I couldn’t even pronounce it at first,” O’Donnell said, when asked about how it helped with her nearly 30kg weight loss. Rosie O’Donnell and Christopher Ketner (Maja Smiejkowska/PA)It is among the weight-loss drugs to have hit the headlines in recent years, with O’Donnell among stars including Jeremy Clarkson, Dame Prue Leith and Sharon Osbourne to reveal they have taken the medication. O’Donnell rose to fame after appearing on US talent show Star Search in the 1980s, and went on to host The Rosie O’Donnell Show from 1996 to 2002 – making her a household name in the country.